ACC in-person meeting reports, diet intervention studies and more

Long-awaited data on salt restriction and nutrition education are on the menu at this weekend’s American College of Cardiology (ACC) meeting, which is welcoming in-person attendees for the first time since the start of the COVID-19 pandemic.

The meeting will take place in Washington, DC, and will also offer virtual streaming and attendance at select sessions.

Among the ACC’s late-breaking scientific presentations scheduled for Saturday is SODIUM-HF, the largest and longest-running randomized trial of sodium restriction in patients with heart failure. If nutritional counseling reduces sodium intake and reduces major adverse events or hospitalizations at 1 year, SODIUM-HF could be the study that strengthens the limited evidence base for reducing dietary salt.

Primary prevention guidelines currently recommend limiting salt, but do not endorse a specific target daily amount.

The SuperWIN trial, which tested how nutrition education sessions in grocery stores, combined with online tools, could help people adhere to the heart-healthy diet Dietary Approaches to Stop Hypertension (DASH) is also outstanding at this year’s ACC meeting. A partnership with supermarket chain Kroger allowed researchers to determine how participants’ eating habits changed after 3 months based on their grocery shopping data. SuperWIN will be presented on Sunday during a last minute test session.

Other highlights of the scientific program include:

  • VALOR-HCM: phase III trial evaluating mavacamten in patients with symptomatic hypertrophic obstructive cardiomyopathy; early results previously announced with cardiac myosin inhibitor apparently reducing need for septal reduction therapy at week 16
  • POISE-3: In this large trial, tranexamic acid is tested for the prevention of bleeding in non-cardiac surgery

  • PROTECT: Also in the non-cardiac surgery setting, this study examined intraoperative hypothermia versus aggressive warming to 98.6ºF to determine what is associated with less myocardial damage at 30 days.

  • CHAP: In this randomized trial, pregnant women with chronic hypertension are treated with a target blood pressure target of 140/90 mm Hg, with pregnancy outcomes compared to untreated controls

  • PROMPT: A Cluster-Randomized Trial of Using Electronic Health Record Alerts to Improve Medical Treatment Prescribing for Heart Failure
  • TRANSLATE-TIMI 70: A dose-finding study evaluating the lipid-lowering effects of vupanorsen, an antisense oligonucleotide inhibiting ANGPTL3 synthesis

  • FLAVOR: a direct comparison of fractional flow reserve versus intravascular ultrasound to guide angioplasty in people with intermediate coronary stenosis

On Friday, the day before the ACC meeting kicks off, updated guidelines on heart failure will be released. A Saturday session will be dedicated to the new recommendations.

The conference comes at a time when states across the United States are easing their pandemic restrictions, despite the spread of the Omicron BA.2 subvariant.

For a safe return to an in-person meeting experience, ACC organizers require attendees to provide proof of full COVID vaccinations (reminder optional), which will be verified when they pass through any of the four checkpoints. physical health and safety screening. Additionally, masks must be worn in the convention center.

  • Nicole Lou is a reporter for MedPage Today, where she covers cardiology news and other developments in medicine. To follow


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